Background Supporting physicians in Intensive Care Units s as they face dying patients at unprecedented levels due to the COVID-19 pandemic is critical. Amidst a dearth of such data and guided by evidence that nurses in ICUs experience personal, professional and existential issues in similar conditions, a systematic scoping review is proposed to evaluate prevailing accounts of physicians facing dying patients in ICUs through the lens of Personhood. Such data would enhance understanding and guide the provision of better support for (...) ICU physicians. Methods An SSR adopts the Systematic Evidenced Based Approach to map prevailing accounts of caring for dying patients in ICUs. To enhance the transparency and reproducibility of this process, concurrent and independent use of tabulated summaries, thematic analysis and directed content analysis is adopted. Results Eight thousand three hundred fifty-eight abstracts were reviewed from four databases, 474 full-text articles were evaluated, 58 articles were included, and the Split Approach revealed six categories/themes centered around the Innate, Individual, Relational and Societal Rings of Personhood, conflicts in providing end of life care and coping mechanisms employed. Conclusion This SSR suggests that caring for dying patients in ICU impacts how physicians view their personhood. To resolve conflicts within individual concepts of personhood, physicians use prioritization, reframing and rely on accessible, personalized support from colleagues to steer coping strategies. An adapted form of the Ring Theory of Personhood is proposed to direct timely personalized, appropriate and holistic support. (shrink)

It is evident, in the face of the COVID-19 pandemic that has physicians confronting death and dying at unprecedented levels along with growing data suggesting that physicians who care for dying patients face complex emotional, psychological and behavioural effects, that there is a need for their better understanding and the implementation of supportive measures. Taking into account data positing that effects of caring for dying patients may impact a physician’s concept of personhood, or “what makes you, ‘you’”, we adopt Radha (...) Krishna’s Ring Theory of Personhood (RToP) to scrutinise the experiences of physicians working in intensive care units (ICU) using a fictional scenario that was inspired by real events. The impact of death and dying, its catalysts, internal constituents, external factors, dyssynchrony, and buffers, specific to ICU physicians, were identified and explored. Such a framework allows for ramifications to be considered holistically and facilitates the curation of strategies for conflict resolution. This evaluation of the RToP acknowledges the experience and wide-ranging effects it has on ICU physicians. As such, our findings provide insight into their specific needs and highlight the importance of support on a personal and organisational level. Although further research needs to be conducted, the RToP could serve as the basis for a longitudinal assessment tool supported by the use of portfolios or mentorship due to their provision of personalised, appropriate, specific, timely, accessible and long-term support. (shrink)

This article proposes a moderated mediation model of emotional dissonance. In the model, emotional leadership negatively affects emotional dissonance, which, in turn, negatively affects helping behavior. Furthermore, the negative effect of emotional dissonance is assumed to be moderated by work-family conflict. Direct effects from both emotional leadership and work-family conflict to helping other behavior are also considered. Previous studies have neglected the mechanism of emotional dissonance, but this paper fills the gap with a moderated mediation model of emotional dissonance. This (...) article not only provides an incremental contribution to the emotional dissonance literature but also suggests means by which companies might enhance employe helping behaviors in order to achieve greater organizational efficiency. (shrink)

What the authors attempt to address in this paper is a Kantian question: not whether, but how is cross -cultural understanding possible? And specifically, what is a more effective approach for cross -cultural understanding? The answer lies in an analysis of two different models of cross -cultural understanding, that is, propositional and hermeneutic understanding. To begin with, the author presents a linguistic interpretation of culture, i.e., a culture as a linguistically formulated and transmitted symbolic system with its conceptual core as (...) a scheme of basic cultural presuppositions, which it referred to as a cultural language. After exploring the essential role of cultural presuppositions in cross -cultural understanding, the author discusses the traditional model of cross -cultural understanding, namely, the propositional model. Through critically examining the two popular versions of the propositional model, i.e., the projective approach and the adoptive approach to cross -cultural understanding, it is found that cross -cultural propositional understanding is doomed to failure. To move us beyond the absolutism -relativism trap embedded within propositional understanding, the author first introduces and discusses Hans-Georg Gadamer’s hermeneutic understanding, and then applies Hans-Georg Gadamer’s hermeneutic model of understanding to cross -cultural understanding. It is finally concluded that cross -cultural understanding is essentially hermeneutic—including the case of cultural learning, not propositional. Therefore, cross -cultural understanding is hermeneutically possible. (shrink)

The current discussions of conceptual schemes and related topics are misguided; for they have been focused too much on the truth-conditional notions of meaning/concepts and translation/interpretation in Tarski's style. It is exactly due to such a Quinean interpretation of the notion of conceptual schemes that the very notion of conceptual schemes falls prey to Davidson's attack. We argue that what should concern us in the discussions of conceptual schemes and related issues, following the initiatives of I. Hacking, T. Kuhn, and (...) N. Rescher, is not the truth-values of assertions, but rather the truthvalue-status of the sentences used to make the assertions. This is because the genuine conceptual innovation between alternative theories/languages does not lie in differences in determining the truth-values of their sentences, but turns on whether these sentences have truth-values when considered within the context of a competing one. The core of conceptual relativism does not consist in the claim that different conceptual schemes may yield incommensurable truth claims, but rather that different conceptual schemes may yield incompatible truth-value-status and therefore lead to distinct perceptions of reality. Conceptual schemes are no longer seen as sentential languages consisting of a set of sentences accepted as true, but rather seen as metaphysical presuppositions of presuppositional languages.[ABSTRACT FROM AUTHOR]. (shrink)

Bayesian networks can be employed to cognitive diagnostic assessment. Most of the existing researches on the BNs for CDA utilized the MCMC algorithm to estimate parameters of BNs. When EM algorithm and gradient descending learning method are adopted to estimate the parameters of BNs, some challenges may emerge in educational assessment due to the monotonic constraints cannot be satisfied in the above two methods. This paper proposed to train the BN first based on the ideal response pattern data contained in (...) every CDA and continue to estimate the parameters of BN based on the EM or the GD algorithm regarding the parameters based on the IRP training method as informative priors. Both the simulation study and realistic data analysis demonstrated the validity and feasibility of the new method. The BN based on the new parameter estimating method exhibits promising statistical classification performance and even outperforms the G-DINA model in some conditions. (shrink)

The eukaryotic genome is organized into different domains by cis‐acting elements, such as boundaries/insulators and matrix attachment regions, and is packaged with different degrees of condensation. In the M phase, the chromatin becomes further highly condensed into chromosomes. The first step for transcriptional activation of a given gene, at a particular time during development, in any locus, is the opening of its chromatin domain. This locus needs to be kept in this state in each early G1 phase during every cell (...) cycle. Certain distal enhance elements, including locus control regions (LCRs) and enhancers, are believed to perform this target chromatin domain opening process and several models have been proposed to explain distal enhance action. But they did not explain precisely how a given chromatin domain is opened. Based on various studies, we propose a hypothesis for the mechanism of opening chromatin on a large scale. One important mechanism may involved breaking one or two DNA strands and reducing the linking numbers within chromatin domain. The topological changes can overpass some complexes formed on DNA strands and can be transmitted from specific localized points over a broad region, until boundary elements or insulators are reached. These may initiate downstream events such as propagation of histone acetylation and the binding of transcription factors to proximal promoters and may further augment the action mediated by distal enhancer elements. BioEssays 25:507–514, 2003. © 2003 Wiley Periodicals, Inc. (shrink)

Background The use of lengthy, detailed, and complex informed consent forms is of paramount concern in biomedical research as it may not truly promote the rights and interests of research participants. The extent of information in ICFs has been the subject of debates for decades; however, no clear guidance is given. Thus, the objective of this study was to determine the perspectives of research participants about the type and extent of information they need when they are invited to participate in (...) biomedical research. Methods This multi-center, cross-sectional, descriptive survey was conducted at 54 study sites in seven Asia-Pacific countries. A modified Likert-scale questionnaire was used to determine the importance of each element in the ICF among research participants of a biomedical study, with an anchored rating scale from 1 to 5. Results Of the 2484 questionnaires distributed, 2113 were returned. The majority of respondents considered most elements required in the ICF to be ‘moderately important’ to ‘very important’ for their decision making. Major foreseeable risk, direct benefit, and common adverse effects of the intervention were considered to be of most concerned elements in the ICF. Conclusions Research participants would like to be informed of the ICF elements required by ethical guidelines and regulations; however, the importance of each element varied, e.g., risk and benefit associated with research participants were considered to be more important than the general nature or technical details of research. Using a participant-oriented approach by providing more details of the participant-interested elements while avoiding unnecessarily lengthy details of other less important elements would enhance the quality of the ICF. (shrink)

ObjectiveBasic combat training is a kind of necessary high-intensity training to help each military recruit convert into a qualified soldier. In China, both the physical fatigue and passive psychological state have been observed in new recruits during BCT. However, after same-intensity training, the degree of fatigue and passive mood vary among recruits. Therefore, this study aimed to explore the effect of BCT on mood state of recruits with different physical fitness levels from a perspective of fatigue.Materials and methodsBefore and after (...) BCT, the degree of fatigue and mood state of participants were evaluated via the Borg Rating of Perceived Exertion Scale and Profile of Mood States Questionnaire immediately after 20 push-ups as RPE and POMS scores [total mood disturbance, passive mood and positive mood ]. The participants were divided into two groups according to the RPE score measured after BCT: group 1: RPE score after BCT < 13 and group 2: RPE score after BCT ≥ 13.ResultA total of 564 recruits were included. After BCT, in group 1, TMD and passive mood Ttension, Tfatigue, Tdepression, Tconfusion declined significantly, but positive mood both increased significantly ; while in group 2, only Tanger and Testeem increased significantly.ConclusionBCT could alleviate passive mood and add to positive mood for recruits with better physical fitness, while had no ameliorative effects on or even deteriorate most of the passive mood for recruits with worse physical fitness. (shrink)

© 2015, Springer-Verlag Berlin Heidelberg.Genetic studies have identified single nucleotide polymorphisms associated with the risk of prostate cancer. It remains unclear whether such genetic variants are associated with disease aggressiveness. The NCI-SPORE Genetics Working Group retrospectively collected clinicopathologic information and genotype data for 36 SNPs which at the time had been validated to be associated with PC risk from 25,674 cases with PC. Cases were grouped according to race, Gleason score and aggressiveness. Statistical analyses were used to compare the frequency (...) of the SNPs between different disease cohorts. After adjusting for multiple testing, only PC-risk SNP rs2735839 was significantly and inversely associated with aggressive and high-grade disease in European men. Similar associations with aggressive and high-grade disease were documented in African-American subjects. The G allele of rs2735839 was associated with disease aggressiveness even at low PSA levels in both European and African-American men. Our results provide further support that a PC-risk SNP rs2735839 near the KLK3 gene on chromosome 19q13 may be associated with aggressive and high-grade PC. Future prospectively designed, case-case GWAS are needed to identify additional SNPs associated with PC aggressiveness. (shrink)

This article examines the operation of “skilled feelings” in metaphors for the heart-mind (xin 心) as ruler of the body. It focuses on three Chinese philosophical texts in contexts outside of the “Confucian” texts that have dominated the emerging field of comparative virtue ethics—the Zhuangzi 莊子, Sunzi Bingfa 孫子兵法 (Sunzi’s Art of War), and Huangdi Neijing 黃帝內經 (The Yellow Emperor’s Classic of Internal Medicine)—and briefly contrasts the Chinese accounts to influential Greek metaphors of the mind as ruler of the body (...) and passions. (shrink)

本书分析了以人生价值观为核心内容的精神教育的困境与出路,论证了通过美育进行人生价值观教育的必要性和可能性。.

In lieu of an abstract, here is a brief excerpt of the content:Feminist Studies 47, no. 2. © 2021 by Feminist Studies, Inc. 251 7 preface 8 In recent years, people all over the world have become ever more aware of being drawn into intimate—and unequal—relations with one another, whether through environmental crises, the COVID-19 pandemic, global economic commodity chains, violent conflicts, forced displacements, or political protests and social movements. This special issue features China’s so-called rising presence as one of (...) the key nodes in these global intimacies. The essays by Mei-Hua Chen and Hong-zen Wang, Sealing Cheng, and Wei Wei contribute new approaches to migrant intimacies across borders through their ethnographically rich analyses. Chen and Wang explore cross-border marriages and sex work between Taiwanese men and Mainland Chinese and southeast Asian women; Cheng investigates refugee marriages and the difficulties men from various African nations face in seeking asylum in Hong Kong; and Wei analyzes Mainland Chinese queer reproduction that uses transnational Assisted Reproductive Technologies (ARTs) to enable queer parents to have a genetic link with their children and to be more accepted in Chinese society. In his essay, Petrus Liu pushes us to move beyond the idea that a theory of gender construction traveled to China from the West and was wholly adopted there, instead demonstrating the complexities of gender theories in China in the age of the Beijing Consensus. Christina Yuen Zi Chung and Sasha Su-Ling Welland explore a broad range of artworks that critically reflect on China’s efforts to create a China-centered global Global Intimacies: China and/in the Global South 252Preface trading network. Paul Amar offers a “deimperial queer analysis” of the all-time top-earning Chinese film, Wolf Warrior 2, illuminating how it both buttresses China’s extractive and militarized investments in African nations and manifests anti-imperialist and utopian impulses. Poems by Zhai Yongming and Xu Lizhi feature the gendered and sexualized precarity and violence of recent social transformations in China resulting from China’s intimate linkages with the global capitalist economy. Finally, Cai Yiping’s News and Views offers a nuanced engagement with the Chinese government’s formal proclamations on women’s rights.1 In the first essay, “Flexible Intimacies in the Global Intimate Economy : Evidence from Taiwan’s Cross-Border Marriages,” Mei-Hua Chen and Hong-zen Wang demonstrate the fallacy of treating cross-border marriages and cross-border sex work as separate as well as grouping women dichotomously under one or the other set of practices. These two seemingly disparate categories are, in effect, produced by state immigration regulations and dominant intersectional discourses of gender, sexuality, and class. Rather than distinguishing between marriage migrants and economic migrants, or between real marriages and fake marriages, Chen and Wang demonstrate the overlapping means by which women from the Global South try to better their lives in what they call the global intimate economy—where the Global North appropriates the reproductive and intimate labor of women from the Global South. The authors develop the concept of “flexible intimacy” to highlight how migrant women treat marriage as an investment through which to improve their lives. They argue that many marriage migrants have economic motivations for cross-border marriage and that migrant sex workers, conversely, are often involved in intimate relationships. Chen and Wang focus their study on Taiwan, which they argue is economically part of the North but politically part of the South due to Mainland China’s “One China” policy, which has marginalized Taiwan in the international political arena. To assert its sovereignty, the Taiwanese government 1. These essays grew out of a Ford Foundation-funded series of workshops on China and/in the Global South: The Central Role of Gender and Sexuality, which took place in Beijing and also at the University of California, Santa Cruz. Thanks to the Ford Foundation grants, and especially Susie Jolly, Lisa Rofel and the authors have built a transnational network of scholars and activists addressing China’s transformed presence in the Global South. Preface 253 strictly controls border crossings by migrant women from China and Southeast Asia yet simultaneously allows Taiwanese husbands to appropriate migrant women’s intimate and reproductive labor. Both Taiwanese men and migrant women expect... (shrink)

Discussing the relations between ethics and aesthetic judgement.

從人類知識的本質、語言的本質、思考的本質進行探索，期待在問題的深處重新尋找問題的新方向。然而，這一切問題的產生、探索的過程、不滿足的感覺、好奇心、徬徨、疑惑等等都有一個相同的來源，當我們深入到問題的核 心地帶，我們突然發現，一切的解答可能都在－－「心靈」 。 本書將會有條不紊、層次分明的帶領讀者來仔細探討這一哲學問題、理論或論證，讓你很快的具備一些基本知識與思路來迎接新知識的衝擊與挑戰。在當代，除哲學外，心理學、電腦科學、人類學、語言學、腦神經科學等等紛紛 加入了這個論戰，這個當代西方最熱門的『意識問題』－－「心靈是什麼？」 本書特色 讓本書告訴你哲學上最核心的問題－－「心靈是什麼？」.

本书记录了笔者跋涉的足迹,主体部分是哲学、美学与文艺学三层次的系列论稿,附录部分收入几则治学礼记。.

本书从分析哲学、新实用主义、实在论、心灵哲学、知识论、道德与政治哲学、美国的马克思主义哲学等七个方面对当代美国哲学的现状、发展趋势进行了一种追踪式的研究。.

本书内容包括:儒家与人际关系的改善;谈儒家与心灵生活;谈孟子与成功之道;感悟老子的人生大智慧等。.

哲學巨擘傅佩榮，獻給愛智者最真摯的禮物 總結懸命半生的重磅著作，橫跨2600年、120位哲學家 ➢哲學就是愛智慧，陪你思考人生問題，掌握人生方向； ➢哲學就是人生經濟學，用最少時間，達成最大效果。 哲學有益人生。傅佩榮教授於「得到」知識平臺開設熱門課程： 「傅佩榮的西方哲學課」，超過四萬訂戶。 本著作為此課程整理修訂而成，完整梳理西方哲學史2600年的120位代表人物， 一套三冊，分為： ．上：古代＋中世紀—介紹古希臘與中世紀哲學 ．中：近代—介紹近代哲學 ．下：現代—介紹現代哲學 本冊為【上：古代＋中世紀】 本著作是哲普作品，也是西方哲學簡史，清楚表述哲學家在愛智過程中所領悟的心得， 與對現代人生的啟發，綜合哲學家用生命驗證的成果，展示西方的核心理念， 讓我們在品味西方哲學時，還能建立起自己的宇宙觀、人生觀、價值觀。 ||上：古代＋中世紀|| 如何讓神從神壇走向廚房？擁有魔戒，你會做什麼？ 悲劇可以淨化心靈嗎？享樂主義的快樂清單說什麼？ 若我受騙，則我存在？有多少力量，就有多少愛？ 古希臘哲學留給後世無限寶貴財富，探討宇宙及萬物的來源； 接續的中世紀哲學由基督宗教主導，綿延1300年， 卻被稱為「黑暗時代」，哲學成為神學的女僕。 但不能忽略基督宗教維持社會穩定、保存文化命脈、塑造西方心靈、 助人面對人生奧祕，是開啟近代哲學的關鍵時期！ ◤哲學讓人生更香甜，改變你對生命的想像！ ．未經反省檢查的人生，是不值得活的。──蘇格拉底 ．對自我有強烈的執著，是一切罪惡的最常見來源。──柏拉圖 ．從事哲學思考，就是學習如何死亡。──西塞羅 ．不要滿不在乎的過日子，好像你可以活一千年似的。──奧雷流士 ．不要從你自身離去，因為真理棲息於人的內心世界。──奧古斯丁 ．人的良心，就是為他引航的最佳嚮導。──司各特 ||書籍特色|| ☆每節結束附上「學習心得」、「問題思考」、「補充說明」， 便於讀者複習重點、換位思考哲學家的觀點進而迸出心靈火花、補充說明關鍵概念。 ☆書中加入作者長年研究儒家與道家的心得，有助讀者在對照比較中， 既可欣賞西方哲學，又能覺悟中國哲學的特色與價值。 ☆書末附有索引，詳列詞條在各冊的頁碼，方便讀者對照查找。.

本书旨在以女性主义视角围绕着性别与哲学进行探索，不仅试图在各种复杂的理论纷争中梳理和澄清诸如性别与社会性别、女性、女性主义、性别差异、妇女哲学、女性主义哲学等基本概念，也对女性主义哲学的产生和发展、学 科定位以及方法论进行分析。.